NEWS on implant innovations

3D blood vessel printing (research)

Scientists in Kiel have developed a innovative 3D bio-printer to create fine blood vessels for bypass implants. "Especially for heart patients who do not have suitable endogenous veins for harvesting a bypass vessel, this new procedure could represent an enormous advance for heart bypass surgery, particularly in terms of patient...

3D printing enters brave new world

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3D printing technologies for soft and hard tissue regeneration

Typically, manufacturing technology is done in four steps: creating or scanning, converting to a file, specifying the print material, and manufacturing. The production of artificial tissues using 3D printing is known as bioprinting. The most common method is the top-down approach. Recently, the bottom-up proceeding has also been successful. Certain...

3D printing to aid tissue replacement

Professor Arda Gozen looks to a future someday in which doctors can hit a button to print out a scaffold on their 3-D printers and create custom-made replacement skin, cartilage, or other tissue for their patients. Gozen, George and Joan Berry associate professor in the Washington State University School of...

An enzymatic pathway that converts A to universal O type blood

An enzymatic pathway in the human gut microbiome that converts A to universal O type blood Access to efficient enzymes that can convert A and B type red blood cells to ‘universal’ donor O would greatly increase the supply of blood for transfusions. Here we report the functional metagenomic screening...

Auditory brainstem implants – hearing restoration in congenitally deaf children

Children born deaf can learn to hear and speak with a cochlear implant (CI). If implantation of a CI is impossible for anatomical reasons, the auditory brainstem implant (ABI) is the only surgical alternative for hearing rehabilitation. Calculations show that about 5-45 children in Germany could be eligible for this...

Biocompatible mini energy storage device for direct diagnosis in the body

Miniatur-Sensoren, die Vitalwerte direkt im Körper bestimmen sollen, sind hochkomplexe Systeme. Eine der größten Hürden stellt die Energieversorgung dar. An der TU Chemnitz haben Wissenschaftler jetzt Energiespeicher entwickelt, die zwar nur so groß wie ein Staubkorn sind, aber Spannungen vergleichbar mit einer AAA-Batterie liefern. Biosuperkondensatoren (BSCs)“. Sie besitzen zwei herausragende...

bioprinting tissue-like constructs capable of controlled, complex shape change

Where standard 3D printing uses a digital blueprint to manufacture an object out of materials like plastic or resin, 3D bioprinting manufactures biological parts and tissues out of living cells, or bioinks. A fourth dimension — shape transformation over time — can be achieved by incorporating materials that enable printed...

Bioprinting- 3D printing of lung scaffolds

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Bone growth inspired “microrobots” that can create their own bone

Inspired by the growth of bones in the skeleton, researchers at the universities of Linköping in Sweden and Okayama in Japan have developed a combination of materials that can morph into various shapes before hardening. The material is initially soft, but later hardens through a bone development process that uses...

Brain implant enables ALS patients to communicate with the world outside

A patient in the advanced stages of amyotrophic lateral sclerosis (ALS) who had lost his last ability to communicate with the outside world after paralyzing his eye muscles has learned to make himself heard again with the help of a brain-computer interface. Nach dem in Nature Communications (2022; DOI: 10.1038/s41467-022-28859-8) vorgestellten Fall­bericht konnte...

Controlled release of soy isoflavones from multifunctional 3D printed bone tissue engineering scaffolds

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Converting blood type A donor lungs into universal blood type lungs

Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs A major challenge in lung transplantation is the need for ABO blood group matching. To address this challenge, Wang et al. used two enzymes, FpGalNAc deacetylase and FpGalactosaminidase, to convert blood group A lungs to blood group...

Dassault Systèmes’ Living Heart Project Reaches Next Milestones

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Digital light 3D printing of customized bioresorbable airway stents

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FRESH 3D Bioprinting a Full-Size Model of the Human Heart

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Fully implantable and bioresorbable cardiac pacemakers without leads or batteries

Temporary cardiac pacemakers used in periods of need during surgical recovery involve percutaneous leads and externalized hardware that carry risks of infection, constrain patient mobility and may damage the heart during lead removal. Here we report a leadless, battery-free, fully implantable cardiac pacemaker for postoperative control of cardiac rate and...

High-performance brain-to-text communication via handwriting

Brain–computer interfaces (BCIs) can restore communication to people who have lost the ability to move or speak. So far, a major focus of BCI research has been on restoring gross motor skills, such as reaching and grasping or point-and-click typing with a computer cursor. However, rapid sequences of highly dexterous...

Hip replacement: virtual surgical training with haptic technology (Interview)

Surgeons have only limited options to practice surgical techniques before they enter the operating room. The implantation of an endoprosthesis requires extensive practical training since it necessitates strength and utmost precision. The "Dynamic HIPS" project develops a virtual reality hip implant simulator that provides realistic haptic feedback. The project has been running...

Implanted System for Orthostatic Hypotension in Multiple-System Atrophy

Orthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods. We implanted a system to restore regulation of blood pressure and enable a patient with multiple-system atrophy to stand and walk after having...

Implants: When technology makes sense – quite literally

Disease, injury, or a condition you were born with – reasons why some people must live without one or several of their five senses. Fortunately, there are many modern sensory aids that help replace one sense with another, which is especially the case when it comes to vision and hearing....

Intestinal plasters

Biocompatible hydrogel technology prevents leakage In future, a new patch could be used after intestinal surgery to prevent leakage into the abdominal cavity. In this video interview, Dr. Alexandre Anthis from ETH Zurich explains the advantages of the hydrogel patch, both from a medical and an economic point of view....

Magnet-controlled bioelectronic implant could relieve pain

A team of Rice University engineers has introduced the first neural implant that can be both programmed and charged remotely with a magnetic field. The integrated microsystem, called MagNI (for magnetoelectric neural implant), incorporates magnetoelectric transducers. These allow the chip to harvest power from an alternating magnetic field outside the...

Medtronic launches InterStim neurostim leads in U.S.

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Microimplants should enable new therapies against common diseases

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Microimplants: electricity instead of pills (Interview)

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Nerve stimulation with the help of implantable mini solar cells

An international research team has successfully developed and tested a concept in which nerves are stimulated with light pulses. The method provides considerable advantages for medicine and opens up a wide range of possible applications. The researchers see possible applications in severe brain injuries. Here, the stimulation of nerve cells...

Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria

Technology to restore the ability to communicate in paralyzed persons who cannot speak has the potential to improve autonomy and quality of life. An approach that decodes words and sentences directly from the cerebral cortical activity of such patients may represent an advancement over existing methods for assisted communication. In...

Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria

Technology to restore the ability to communicate in paralyzed persons who cannot speak has the potential to improve autonomy and quality of life. An approach that decodes words and sentences directly from the cerebral cortical activity of such patients may represent an advancement over existing methods for assisted communication. We...

Novel brain pacemaker first used for the treatment of obsessive-compulsive disorder (OCD)

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Paving the Way for Electronic Organs-on-a-Chip

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Perfectly fitting knee joints from the 3-D printer

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Platform for testing, development and approval of cardiovascular implants planned

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Poietis Automates the Manufacturing of Biological Tissue

While the manufacturing of biological tissue meets major societal demands, it also faces significant challenges related to process standardization and scaling up. With these challenges in mind, the French start-up Poietis has developed the Next Generation Bioprinting (NGB) platform to achieve 4D bioprinting of biological tissue in a faster, more affordable and more functional...

Research network in Hanover conducts research on intelligent implants

Researchers from a wide range of disciplines will work together to develop intelligent implant systems for the dental, skeletal and hearing areas, which for the first time will allow continuous monitoring of implant function and thus early detection of complications such as infections. Intelligent implant systems are to be developed...

Retina chip implanted

A team led by Frank Holz, director of the Department of Ophthalmology at Bonn University Hospital (UKB), has implanted a retinal chip in a patient with advanced dry age-related macular degeneration (AMD) to preserve his vision. AMD is a visual disorder that increases with age and is characterized by progressive...

Self-healing capacity of fiber-reinforced calcium phosphate cements

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Sights on implantable ‘living pharmacy’

Five Rice University engineering laboratories are part of a $33 million national effort to develop a wireless, fully implantable device that can control the body’s circadian clock, halving the time it takes to recover from jet lag and similar disruptions to the body’s sleep/wake cycles. Led by Northwestern University and...

Spelling interface using intracortical signals enabled neurofeedback training

Spelling interface using intracortical signals in a completely locked-in patient enabled via auditory neurofeedback training Patients with amyotrophic lateral sclerosis (ALS) can lose all muscle-based routes of communication as motor neuron degeneration progresses, and ultimately, they may be left without any means of communication. Here, we implanted two 64 microelectrode...

Spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

Three people once paralysed by complete spinal-cord injuries can walk, swim, work the pedals of a bicycle and even paddle canoes, thanks to an implant that stimulates neurons in their spinal cords. Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments restores walking in people with spinal cord...

The Kidney Project successfully tests a prototype bioartificial kidney

The Kidney Project’s implantable bioartificial kidney, one that promises to free kidney disease patients from dialysis machines and transplant waiting lists, took another big step toward becoming reality, earning a $650,000 prize from KidneyX for its first-ever demonstration of a functional prototype of its implantable artificial kidney. The Kidney Project’s...

Tracking Lab-Grown Tissue With Light

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When the pacemaker is hacked

Cybercrime against healthcare facilities is on the rise, and the networking of medical devices opens up numerous gateways for hackers. To protect patients and facilities, all players must cooperate, and the manufacturers of medical devices have a special role to play. Modern hospitals and other healthcare facilities depend on functioning...