An enzymatic pathway that converts A to universal O type blood

An enzymatic pathway in the human gut microbiome that converts A to universal O type blood

Access to efficient enzymes that can convert A and B type red blood cells to ‘universal’ donor O would greatly increase the supply of blood for transfusions. Here we report the functional metagenomic screening of the human gut microbiome for enzymes that can remove the cognate A and B type sugar antigens.
Author(s)Source
Rahfeld P, Sim L, Moon H et al.Nat Microbiol 4, 1475–1485 (2019), doi.org/10.1038/s41564-019-0469-7
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