Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria
|Technology to restore the ability to communicate in paralyzed persons who cannot speak has the potential to improve autonomy and quality of life. An approach that decodes words and sentences directly from the cerebral cortical activity of such patients may represent an advancement over existing methods for assisted communication.|
|We implanted a subdural, high-density, multielectrode array over the area of the sensorimotor cortex that controls speech in a person with anarthria (the loss of the ability to articulate speech) and spastic quadriparesis caused by a brain-stem stroke.|
In a person with anarthria and spastic quadriparesis caused by a brain-stem stroke, words and sentences were decoded directly from cortical activity during attempted speech with the use of deep-learning models and a natural-language model.
|Moses DA, Metzger SL, Liu JR et al.||July 15, 2021, N Engl J Med 2021; 385:217-227, DOI: 10.1056/NEJMoa2027540|
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