Depression, Antidepressants, and Bone Health in Older Adults

Depression, Antidepressants, and Bone Health in Older Adults: A Systematic Review
Depression and depressive symptoms are associated with low bone mass and accelerated bone loss in older adults; putative mechanisms underlying this relationship are discussed. There is insufficient evidence that SRI antidepressants adversely affect bone health. Thus, a change in current recommendations for the use of antidepressants in older adults is not justified at the present time. Given the high public health significance of this question, more studies are required to determine whether (and in whom) antidepressants may be deleterious for bone health.
Author(s) Source
Gebara MA, Shea MLO, Lipsey KL et al. Journal of American Geriatric Society, 15 Jul 2014, https://doi.org/10.1111/jgs.12945
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