Esophageal Organoids from Human Pluripotent Stem Cells

Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification	SL Trisno et al.
Highlights • Sequential Wnt, RA, and BMP signaling are required to pattern dorsal anterior foregut • Cultured dorsal anterior foregut spheroids develop into esophageal organoids (HEOs) • HEOs contain basal esophageal progenitors and stratified squamous epithelium • Sox2 is sufficient to repress the respiratory fate by suppressing Wnt signaling	ScienceDirect 4 Oct 2018
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Highlights