Which antibiotics for endocarditis prophylaxis in oral implantology?

Endocarditis is an infectious disease of the inner lining of the heart (endocardium). It is frequently associated with severe progression (high morbidity) and often with a poor prognosis (high mortality). Therefore, antibiotics have been prescribed for prophylaxis in patients with a risk profile for endocarditis for more than 50 years. This antibiotic prophylaxis, which has been established for many years, aims to intercept bacteremia during invasive procedures in the oral cavity to reduce the risk of endocarditis.
Single dose protocol: 30 – 60 minutes before the procedure:
oral Amoxicillin
not possible top take orally Ampicillin or Cefazolin or Ceftriaxone
allergy to penicillin or ampicillin – oral Cefalexin or Azithromycin or Clarithromycin or Doxycyclin
allergy to penicillin or ampicillin – no oral intake possible Cefazolin or Ceftriaxone
Pay attention to exact dosage and instructions in the original article.
According to the largely uniform recommendations of the American Heart Association in 2007 and the European Society of Cardiology in 2009, endocarditis prophylaxis should only be used in patients who belong to the following risk groups:
  • survived endocarditis
  • artificial heart valves
  • patients with the following congenital heart defects:
    a) non-treated heart defects
    b) treated heart defects with residual defects
    c) heart defects repaired with artificial material
  • after heart transplantation
Author(s) Source
Bilobrk P, Grötz KA ZZI 3/2022, DOI.org/10.53180/ ZZI.2022.0142–0144 (german original)
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