biphasic calcium sulfate dihydrate (CSD)
The medical use of Calcium Sulfate has the longest history in the augmentation field, with over 120 years of use in the areas of Orthopedics, Plastics, Oncology and Maxillofacial medicine.
The initial setting time is approximately 3-5 minutes. The material is completely resorbed within 4-10 weeks, coinciding with the time period it takes for bone to form. The outcome is a complete replacement of the graft with the patient’s own bone. (Augma)
Calcium sulfate resorbs very quickly, usually in 4 to 6 weeks. For this reason, it is recommended, to mix calcium sulfate with other bone substitutes with longer resorption profiles to create a composite-type graft. This is especially the case when there is a larger lesion. The granule type that is mixed with calcium sulfate can be selected according to the clinician’s preference. Many clinicians mix calcium sulfate with allograft, and others use other synthetics like ß-TCP or hydroxyapatite. (“Enhancing extraction socket therapy with a biphasic calcium sulfate. Horowitz RA1, Rohrer MD, Prasad HS, Tovar N, Mazor Z.Compend Contin Educ Dent. 2012 Jun;33(6):420-6, 428.)