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Heterograft

July 15, 2018

see: Xenograft

Currently on this page:

8600 implants
984 companies
587 societies
43 patient information
Latest News
Feasibility Study of the BrainGate Neural Interface System
January 13, 2023Interim Safety Profile From the Feasibility Study of the BrainGate Neural Interface SystemBrain computer interfaces (BCIs) are being developed to restore mobility, communication, and functional independence to people with paralysis. Though supported by decades of preclinical data, the safety of chronically implanted microelectrode array BCIs in humans is unknown. We report safety results from the prospective, open-label, non-randomized BrainGate feasibility study (NCT00912041), the largest and longest-running clinical trial of an implanted BCI. Results: From 2004 – 2021, fourteen adults enrolled in the BrainGate trial had devices surgically implanted. The average duration of device implantation was 872 days, yielding 12,203 days of safety experience. There were 68 device-related adverse events, including 6 device-related serious adverse events. The most common device-related adverse event was skin irritation around the percutaneous pedestal. There were no safety events that required device explantation, no unanticipated adverse device events, no intracranial infections, and no participant deaths or adverse events resulting in permanently increased disability related to the investigational device. Discussion: The BrainGate Neural Interface system has a safety record comparable to other chronically implanted medical devices. Given rapid recent advances in this technology and continued performance gains, these data suggest a favorable risk/benefit ratio in appropriately selected individuals to support ongoing research and development. Author(s) Source Rubin DB, Ajiboye AB, Barefoot L et al. Neurology.org, January 13, 2023, DOI: https://doi.org/10.1212/WNL.0000000000201707 This is a post of a scientific or business information. The information given here is checked thoroughly by “Implant-Register”. However we can´t be responsible for the content. The content usually is shortened to make it understandable for many. Read the linked original text if you are interested. Contact the publisher, if you have questions. You may inform us about changes of the information to improve the Register. Comments: n/alet us know [...] Read more...
Brain stimulation boosts hearing in rats with ear implants
December 21, 2022Study identifies neurons that can improve sound perception, which could explain the variation in performance in people with cochlear devices. Stimulating neurons that are linked to alertness helps rats with cochlear implants learn to quickly recognize tunes, researchers have found. The results suggest that activity in a brain region called the locus coeruleus (LC) improves hearing perception in deaf rodents. Researchers say the insights are important for understanding how the brain processes sound, but caution that the approach is a long way from helping people. Cochlear implants use electrodes in the inner-ear region called the cochlea, which is damaged in people who have severe or total hearing loss. The device converts acoustic sounds into electrical signals that stimulate the auditory nerve, and the brain learns to process these signals to make sense of the auditory world. Some people with cochlear implants learn to recognize speech within hours of the device being implanted, whereas others can take months or years. “This problem has been around since the dawn of cochlear implants, and it shows no signs of being resolved” (Gerald Loeb, USCLA). Researchers caution that stimulating the LC in humans could be dangerous. The region sends signals to many brain regions, and regulates the fight-or-flight response. Stimulating the LC in people “would raise blood pressure and heart rate, and other autonomic responses”, says Graeme Clark, an otolaryngologist in the Graeme Clark Institute at the University of Melbourne, Australia, who developed the first multi-channel cochlear implant in the 1970s. “We would have to do a series of experiments to prove that it is something worth doing.” Author(s) Source Naddaf M nature, 21 Dec 2022doi: https://doi.org/10.1038/d41586-022-04553-z This is a post of a scientific or business information. The information given here is checked thoroughly by “Implant-Register”. However we can´t be responsible for the content. The content usually is shortened to make it understandable for many. Read the linked original text if you are interested. Contact the publisher, if you have questions. You may inform us about changes of the information to improve the Register. Comments: n/alet us know [...] Read more...
Locus coeruleus activity improves cochlear implant performance
December 21, 2022Cochlear implants (CIs) are neuroprosthetic devices that can provide hearing to deaf people. Despite the benefits offered by CIs, the time taken for hearing to be restored and perceptual accuracy after long-term CI use remain highly variable. CI use is believed to require neuroplasticity in the central auditory system, and differential engagement of neuroplastic mechanisms might contribute to the variability in outcomes. Despite extensive studies on how CIs activate the auditory system, the understanding of CI-related neuroplasticity remains limited. One potent factor enabling plasticity is the neuromodulator noradrenaline from the brainstem locus coeruleus (LC). Here we examine behavioural responses and neural activity in LC and auditory cortex of deafened rats fitted with multi-channel CIs. Adequate engagement of central neuromodulatory systems is thus a potential clinically relevant target for optimizing neuroprosthetic device use. Author(s) Source Glennon E Valtcheva S, Zhu A, et al. Nature volume 613, pages317–323 (2023), https://doi.org/10.1038/s41586-022-05554-8 This is a post of a scientific or business information. The information given here is checked thoroughly by “Implant-Register”. However we can´t be responsible for the content. The content usually is shortened to make it understandable for many. Read the linked original text if you are interested. Contact the publisher, if you have questions. You may inform us about changes of the information to improve the Register. Comments: n/alet us know [...] Read more...
Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer’s disease
December 14, 2022Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with mild Alzheimer’s Disease. Outcomes from randomized clinical trials have shown that cognitive function improved in some patients but deteriorated in others. This could be explained by variance in electrode placement leading to differential engagement of neural circuits. To investigate this, we performed a post-hoc analysis on a multi-center cohort of 46 patients with DBS to the fornix. Using normative structural and functional connectivity data, we found that stimulation of the circuit of Papez and stria terminalis robustly associated with cognitive improvement. On a local level, the optimal stimulation site resided at the direct interface between these structures. Finally, modulating specific distributed brain networks related to memory accounted for optimal outcomes. Findings were robust to multiple cross-validation designs and may define an optimal network target that could refine DBS surgery and programming. Author(s) Source Ríos AS, Oxenford S, Neudorfer C et al. Nat Commun 13, 7707 (2022). https://doi.org/10.1038/s41467-022-34510-3 This is a post of a scientific or business information. The information given here is checked thoroughly by “Implant-Register”. However we can´t be responsible for the content. The content usually is shortened to make it understandable for many. Read the linked original text if you are interested. Contact the publisher, if you have questions. You may inform us about changes of the information to improve the Register. Comments: n/alet us know [...] Read more...
New Companies
Senseonics, Inc.
January 22, 2023unregisteredregister now IMPLANTS U.S.A. product group data implant, chip products Eversense® E3 CGM contact n/a This is a post of a nonregistered company. Information given here is checked thoroughly by “Implant-Register”. However we can not guarantee for any material, property or completeness. Products may not be available in all countries. Ask the company for such questions and give us the information to improve the Register. If there are pictures like logos or implants, they may be taken from the companies website. The publishing company may inform us to improve or hide them. [...] Read more...
Dexcom Inc.
January 22, 2023unregisteredregister now IMPLANTS U.S.A. product group data implant, chip (transmitting) products Dexcom G6 ( CGM ) Dexcom G7 ( CGM ) contact n/a This is a post of a nonregistered company. Information given here is checked thoroughly by “Implant-Register”. However we can not guarantee for any material, property or completeness. Products may not be available in all countries. Ask the company for such questions and give us the information to improve the Register. If there are pictures like logos or implants, they may be taken from the companies website. The publishing company may inform us to improve or hide them. [...] Read more...
DIOPTEX
December 28, 2022unregisteredregister now IMPLANTS AUSTRIA product group eye implant products MyoRing complete-ring implant for the treatment of ectatic eye diseases such as keratoconus and complicated cases of shortsightedness contact n/a This is a post of a nonregistered company. Information given here is checked thoroughly by “Implant-Register”. However we can not guarantee for any material, property or completeness. Products may not be available in all countries. Ask the company for such questions and give us the information to improve the Register. If there are pictures like logos or implants, they may be taken from the companies website. The publishing company may inform us to improve or hide them. [...] Read more...
New Implants
MinerOss® A
November 27, 2022IMPLANT PROFILE unregisteredregister here granules blocks plates 01 indication implant, bone substitute for jaw applications like extraction sockets, alveolar defects, alveolar ridge enhancement, sinus augmentation 02 specific natural remodeling, osteoconductive 03 contraindication(s) ◊◊◊◊◊ 04 implant description ◊◊◊◊◊ 05 specific attributes ◊◊◊◊◊ 06 material(s) human femoral bone, origin: Cells+Tissuebank Austria (C+TBA) 07 implant surface n/a 08 key literature ◊◊◊◊◊  09 notes about the company n/a 10 approvals X CE-Marking n/a FDA-Approval ♦ current as of 2022-11-20 unregistered / this page is not approved by the provider / unregistered implants have no professionnal lines or advertising This “Implant Profile” shows a non-registered implant. This is a most comprehensive description of the important parameters of an implant. Information given here are checked thoroughly by “Implant-Register” and is not approved by the manufacturer/the company. Illustrations refer to the company, if not shown differently. However we can not guarantee for any material or properties. Implants may not be available in all countries. If there are pictures like logos or implants, they are taken from the companies website. The publishing company may inform us to hide them.  No comments yet. You are welcome to send comments or experiences.HERE, if you received this implant. and HERE, if you placed this implant. If you have received this implant, you can register it HERE (fee). [...] Read more...
Lenstec, Inc.
November 19, 2022unregisteredregister now IMPLANTS U.S.A. product group eye implant products Capsular Tension Rings Clearview™ multifocal IOL PMMA lenses SBL-2 SBL-3 Softec HP1 Softec Series IOL HD Softec Series IOL HD3 Softec Series IOL HDM Softec Series IOL HDO Softec Series IOL HDY Softec Series IOL I Tetraflex HD contact n/a This is a post of a nonregistered company. Information given here is checked thoroughly by “Implant-Register”. However we can not guarantee for any material, property or completeness. Products may not be available in all countries. Ask the company for such questions and give us the information to improve the Register. If there are pictures like logos or implants, they may be taken from the companies website. The publishing company may inform us to improve or hide them. [...] Read more...
Spectra™ Concealable Penile Prosthesis
October 25, 2022IMPLANT PROFILE unregisteredregister here the implant 01 indication implant for single‐use, intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in men who are determined to be suitable candidates for implantation surgery 02 specific ◊◊◊◊◊ 03 contraindication(s) active urogenital infections or active skin infections in the region of surgery if proximal corporal length measurement is less than the proximal rigid section of the Spectra cylinders poor candidates for surgical procedures and/or anesthesia patients who require repeated endoscopic procedures patients with compromised tissue and as a result cannot withstand constant pressure 04 implant description a pair of semi-rigid cylinders placed inside the penis 05 specific attributes ◊◊◊◊◊ 06 material(s) n/a 07 implant surface n/a 08 key literature ◊◊◊◊◊  09 notes about the company n/a 10 approvals CE-Marking FDA-Approval learn more about approvals, certifications, authorities No comments yet. You are welcome to send comments or experiences.HERE, if you received this implant. and HERE, if you placed this implant. Received this implant? You can register it HERE (fee).Placed this implant? You can register it HERE (fee). current as of 2022-10-25 unregistered / this page is not approved by the provider / unregistered implants have no professionnal lines or advertising This “Implant Profile” shows a non-registered implant. This is a most comprehensive description of the important parameters of an implant. Information given here are checked thoroughly by “Implant-Register” and is not approved by the manufacturer/the company. Illustrations refer to the company, if not shown differently. However we can not guarantee for any material or properties. Implants may not be available in all countries. If there are pictures like logos or implants, they are taken from the companies website. The publishing company may inform us to hide them.  [...] Read more...

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