IMPLANT INFORMATION about Hard Tissue / Platelet Techniques

What … for? (Indications)
Stimulation of the healing of bone and soft tissue, e.g. at tendinopathies, ligament sprains, muscle strains, joints, intervertebral discs, nerves, neurosurgery, fracture non-union, cosmetic surgery, orthopedic surgery, maxillofacial surgery, general surgery
platelet_rich_plasma_figure_03Blood from the patient is collected, centrifuged and the plasma portion rich in growth factors is applied; either as injection or mixed with the material used in a surgery, like bone substitutes.
Numbers n/a
Depending on the material to be stimulated, healing time can be reduced
Risks (Contraindications)Risks from the procedure• Infection
• Bleeding
• Nerve damage
• Pain
• Lack of result
• Loss of injected area/death very rarely
Absolute• Platelet dysfunction syndrome
• Critical thrombocytopenia
• Hemodynamic instability
• Septicemia
• Local infection at the site of the procedure
• Patient unwilling to accept risks
Relative• Consistent use of NSAIDs within 48 hours of procedure
• Corticosteroid injection at treatment site within 1 month
• Systemic use of coriticosteroids within 2 weeks
• Tobacco use
• Recent fever or illness
• Cancer – especially hematopoetic or of bone
• HGB < 10 g/dl • Platelet count < 105/μl
Failuresn/a, too many varieties
Materials availableautologous
Statisticsn/a, too many varieties, evidence hardly to be prooved
LiteratureBasic– Platelet Rich Plasma (PRP) Injection Technique. Hauser RA, Hauser MA. Journal of Prolotherapy, 2009; 1(3):184
– Guidelines for the Us of Platelet Rich Plasma, The International Cellular Medical Society

– Guidelines for the Use of Platelet Rich Plasma– Platelet-Rich Plasma: Properties and Clinical Applications, Smith RG, Gassmann CJ, Campbell MS. The Journal of Lancaster general Hospital, Summer 2007, Vol. 2 – No. 2
ProblemsAutologous Platelet Gel: Fad or Savoir? Do we really know?, Stammers AH, Trowbridge CC, Marko M, Woods EL, Brindisi N, Pezzuto J, Klayman M, Fleming S, Petzold J, The Journal of ExtraCorporal Technology JECT, 2009, 41, 25-30
Science/Futuren/a no recent studies seen
Register (links)n/a
Medical Societiesdealing with this subject are here. 
Platelet techniques are performed in some subspecialties and maybe dealt there.
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