This guidance represents the current thinking of the Food and Drug Administration (FDA or Agency) on this topic. It does

A biomaterial, resorbable or non-resorbable, surgically placed to restore lost bony substance.

A biomaterial, resorbable or non-resorbable, placed surgically on the surface of a bone, with or without loss of tissue, to obtain selective or

Metacarpophalangeal joint

Monocalcium Phosphate Monohydrate

durability Mechanical heart valves can last indefinitely (tested over 50,000 years in an accelerated tester) types Caged-ball valve Tilting-disc valves

Minimally Invasive Cardiac Surgery

Minimally Invasive Surgery

Minimally Invasive Spine (port system or access)

Mesenchyymal Stem Cell

metatarsophalangeal