Gentamicin coating of titanium alloy prevents implant-related osteomyelitis in rats

Gentamicin coating of plasma chemical oxidized titanium alloy prevents implant-related osteomyelitis in rats Biomaterials, Volume 101, issue 0, 156-164
Contamination of implants, bacterial load of bone powder and radiographic as well as histological signs of implant-related osteomyelitis were evaluated after four weeks. Gentamicin-SDS coating prevented implant contamination in 10 of 10 tibiae and gentamicin-tannic acid coating in 9 of 10 tibiae (infection prophylaxis rate 100% and 90% of cases, respectively). M. Diefenbeck, C. Schrader, F. Gras, T. Mückley, J. Schmidt, S. Zankovych, J. Bossert, K.D. Jandt, A. Völpel, B.W. Sigusch